BPC-157

Body Protection Compound-157

Overview

A synthetic peptide derived from gastric protein. Demonstrates tissue repair across tendon, ligament, muscle and gut in peer-reviewed research.

Key Mechanisms

• Upregulates GH receptor expression in tendon fibroblasts

• Promotes angiogenesis at injury sites

• Cytoprotective effects on gastric mucosa

Research Finding

Rodent studies show BPC-157 significantly accelerates Achilles tendon healing with improved tensile strength and collagen organisation. (Krivic et al., 2006)

TB-500

Thymosin Beta-4 Fragment

Overview

A synthetic analogue of Thymosin Beta-4, naturally present in human cells. Plays a critical role in actin regulation with regenerative and anti-inflammatory properties.

Key Mechanisms

• Binds actin monomers to regulate cytoskeletal structure

• Promotes stem cell differentiation and tissue repair

• Downregulates IL-6 and TNF-a inflammatory cytokines

Research Finding

Nature published research showing Thymosin Beta-4 activates dormant epicardial progenitor cells following cardiac injury.

GHK-Cu

Glycine-Histidine-Lysine Copper Complex

Overview

A naturally occurring copper complex in human plasma with over four decades of research. One of the most studied peptides in skin biology and wound healing.

Key Mechanisms

• Stimulates collagen I, III and VII synthesis

• Activates TGF-beta pathway for tissue remodelling

• Modulates 4,000+ human genes associated with repair

Research Finding

Journal of Biomaterials Science studies demonstrate GHK-Cu increases collagen synthesis by up to 70% in fibroblast cultures.

MOTS-c

Mitochondrial Derived Peptide

Overview

A mitochondria-derived peptide discovered in 2015, encoded by mitochondrial DNA. Significant implications for metabolic regulation and longevity research.

Key Mechanisms

• Activates AMPK, master regulator of cellular energy

• Inhibits folate cycle to improve insulin sensitivity

• Increases glucose uptake independent of insulin

Research Finding

Lee et al. Cell Metabolism 2015 demonstrated MOTS-c significantly improves insulin sensitivity in diet-induced obese mouse models.

Retatrutide

GLP-1/GIP/Glucagon Triple Agonist

Overview

First-in-class triple hormone receptor agonist. Phase 2 NEJM data demonstrated unprecedented weight reduction outcomes in metabolic research.

Key Mechanisms

• GLP-1 agonism reduces appetite and slows gastric emptying

• GIP agonism enhances insulin sensitivity

• Glucagon agonism increases energy expenditure

Research Finding

Phase 2 NEJM trial (2023) demonstrated mean weight reduction of 17.5% at 24 weeks, exceeding previously published GLP-1 agonist data.

Tesamorelin

Growth Hormone Releasing Hormone Analogue

Overview

A synthetic GHRH analogue with FDA approval for HIV-associated lipodystrophy. Research focus includes visceral adiposity and cognitive function.

Key Mechanisms

• Binds GHRH receptors to stimulate pulsatile GH release

• Maintains physiological GH pulsatility

• Reduces visceral adipose tissue via GH-mediated lipolysis

Research Finding

Clinical trials demonstrate Tesamorelin reduces visceral adipose tissue by approximately 15-20% versus placebo over 26 weeks.

Tirzepatide

Dual GIP/GLP-1 Receptor Agonist

Overview

FDA-approved dual GIP/GLP-1 agonist. SURMOUNT-1 Phase 3 trial demonstrated up to 22.5% weight reduction, the largest recorded at that time.

Key Mechanisms

• Dual GIP/GLP-1 agonism for synergistic insulin secretion

• GIP enhances adipose metabolism and insulin sensitivity

• Improves beta-cell function in peripheral tissues

Research Finding

SURMOUNT-1 NEJM 2022: mean weight reduction of 22.5% over 72 weeks, the largest recorded in a Phase 3 trial at that time.

NAD+

Nicotinamide Adenine Dinucleotide

Overview

An essential coenzyme central to energy metabolism, DNA repair and cellular signalling. Levels decline significantly with age, a key focus of longevity research.

Key Mechanisms

• Essential cofactor in oxidative phosphorylation

• Activates SIRT1 and SIRT3 longevity deacetylases

• Required for PARP-mediated DNA damage repair

Research Finding

American Journal of Physiology 2024 confirms NAD+ supplementation supports oxidative phosphorylation and ATP production.

GLOW

GHK-Cu / BPC-157 / TB-500 Blend

Overview

A research blend combining GHK-Cu, BPC-157, and TB-500 — three individually studied peptides selected for their combined focus on tissue repair, skin structure, and cellular recovery.

Key Mechanisms

• GHK-Cu stimulates collagen synthesis and tissue remodelling

• BPC-157 studied for gut, tendon, and angiogenic repair pathways

• TB-500 promotes cell migration and cytoskeletal repair

Research Finding

Each component peptide has independent published research individually. GLOW as a combined formulation has not itself been studied in clinical trials.

KLOW

GHK-Cu / BPC-157 / TB-500 / KPV Blend

Overview

Builds on the GLOW blend with KPV added — a tripeptide studied for anti-inflammatory activity — extending the formulation's focus toward recovery and structural performance.

Key Mechanisms

• GHK-Cu, BPC-157 and TB-500 contribute tissue repair and collagen pathways

• KPV studied for modulating inflammatory response via melanocortin receptor activity

• Combined formulation targets joint, muscle and connective tissue research contexts

Research Finding

As with GLOW, each component has independent published research individually. KLOW as a combined formulation has not itself been studied in clinical trials.

CJC-1295 + Ipamorelin

GHRH Analogue / GH Secretagogue Blend

Overview

A combination of CJC-1295, a GHRH analogue, and Ipamorelin, a selective growth hormone secretagogue — studied for their complementary mechanisms in stimulating endogenous growth hormone release.

Key Mechanisms

• CJC-1295 extends GHRH receptor stimulation, prolonging GH pulse duration

• Ipamorelin selectively stimulates the ghrelin receptor with minimal effect on cortisol or prolactin

• Combined use studied for synergistic amplification of GH pulsatility

Research Finding

Preclinical research indicates combining a GHRH analogue with a selective ghrelin receptor agonist produces a synergistic increase in GH secretion beyond either compound alone.

Bac Water

Bacteriostatic Water 0.9%

Overview

The standard reconstitution solution for lyophilised research peptides. Benzyl alcohol prevents bacterial growth allowing multi-dose use when stored correctly.

Key Mechanisms

• 0.9% benzyl alcohol inhibits bacterial growth

• Isotonic formulation minimises injection site irritation

• Compatible with all lyophilised peptides

Research Finding

Maintains reconstituted peptide stability for up to 28 days at 2-8 degrees C versus 24 hours for sterile water without preservative.

Vial Strength 20 mg

Bac Water Added 2.0 mL

Desired Dose MCG MG

Syringe U-100 (100 units / mL) U-50 (50 units / 0.5 mL) U-40 (40 units / mL)

Reset

Draw To

5

units on the syringe